Idoxuridine

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Scientific Name: Idoxuridine
Brand Name: Not Available
Company Owner: Glaxosmithkline, Alcon laboratories inc, Allergan pharmaceutical
Mechanism Of Action Idoxuridine acts as an antiviral agent by inhibiting viral replication by substituting itself for thymidine in viral DNA. This in turn inhibits thymidylate phosphorylase and viral DNA polymerases from properly functioning. The effect of Idoxuridine results in the inability of the virus to reproduce or to infect/destroy tissue.
Description of the Drug: Idoxuridine is a pyrimidine analog antiviral used for the treatment of viral eye infections, including herpes simplex keratitis.
Protein Data Bank:
Source: DrugBank Online – DrugBank.com. Retrieved 2023-01-23 from https://go.drugbank.com/drugs/DB00249