Idarubicin

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Scientific Name: Idarubicin
Brand Name: Idamycin
Company Owner: Not Available
Mechanism Of Action Idarubicin has antimitotic and cytotoxic activity through a number of proposed mechanisms of action: Idarubicin forms complexes with DNA by intercalation between base pairs, and it inhibits topoisomerase II activity by stabilizing the DNA-topoisomerase II complex, preventing the religation portion of the ligation-religation reaction that topoisomerase II catalyzes.
Description of the Drug: Idarubicin is an anthracycline antineoplastic agent used to treat acute myeloid leukemia (AML) in adults.
Protein Data Bank:
Source: DrugBank Online – DrugBank.com. Retrieved 2023-01-23 from https://go.drugbank.com/drugs/DB01177