Idarubicin
Back to search| Scientific Name: | Idarubicin |
| Brand Name: | Idamycin |
| Company Owner: | Not Available |
| Mechanism Of Action | Idarubicin has antimitotic and cytotoxic activity through a number of proposed mechanisms of action: Idarubicin forms complexes with DNA by intercalation between base pairs, and it inhibits topoisomerase II activity by stabilizing the DNA-topoisomerase II complex, preventing the religation portion of the ligation-religation reaction that topoisomerase II catalyzes. |
| Description of the Drug: | Idarubicin is an anthracycline antineoplastic agent used to treat acute myeloid leukemia (AML) in adults. |
| Protein Data Bank: |
Source: DrugBank Online – DrugBank.com. Retrieved 2023-01-23 from https://go.drugbank.com/drugs/DB01177
