Icosapent ethyl

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Scientific Name: Icosapent ethyl
Brand Name: Vascepa
Company Owner: Not Available
Mechanism Of Action Studies suggest that EPA reduces hepatic very low-density lipoprotein triglycerides (VLDL-TG) synthesis and/or secretion and enhances TG clearance from circulating VLDL particles. Potential mechanisms of action include increased β-oxidation; inhibition of acyl-CoA: 1, 2-diacylglycerol acyltransferase (DGAT) ; decreased lipogenesis in the liver; and increased plasma lipoprotein lipase activity.
Description of the Drug: Icosapent ethyl is an ethyl ester of eicosapentaenoic acid (EPA) that reduces synthesis and enhances clearance of triglycerides that is used to treat patients with severe hypertriglyceridemia.
Protein Data Bank: Not Available
Source: DrugBank Online – DrugBank.com. Retrieved 2023-01-23 from https://go.drugbank.com/drugs/DB08887