Hydroxyurea
Back to searchMolecule Structure
Scientific Name
Hydroxyurea
Description of the Drug
Hydroxyurea is an antimetabolite used to treat sickle cell anemia crisis.
Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB01005
http://www.drugbank.ca/drugs/DB01005
Brand Name(s)
Droxia, Hydrea, Hydroxyurea, Siklos
Company Owner(s)
Bristol Myers Squibb Co, Par Pharmaceutical Inc, Addmedica Sas, Roxane Laboratories Inc, Barr Laboratories Inc, Leading Pharma Llc
Mechanism(s) Of Action
| Target Name | Target Type | Action Type | Target ChEMBL ID |
|---|---|---|---|
| Ribonucleoside-diphosphate reductase RR1 | PROTEIN COMPLEX GROUP | INHIBITOR | CHEMBL2095215 |
Clinical Trial(s)
Unichem Links
| Atlas | hydroxyurea | |||||
| SureChEMBL | SCHEMBL19375830 | SCHEMBL4004 | ||||
| PharmGKB | PA449942 | |||||
| Human Metabolome Database | HMDB0015140 | |||||
| DrugBank | DB01005 | |||||
| PubChem: Thomson Pharma | 14747331 | |||||
| PubChem | 3657 | |||||
| Mcule | MCULE-9465284053 | |||||
| NMRShiftDB | 70021631 | |||||
| LINCS | LSM-45988 | |||||
| Nikkaji | J2.937H | |||||
| PDBe | NHY | |||||
| BindingDB | 50017811 | |||||
| EPA CompTox Dashboard | DTXSID6025438 | |||||
| DrugCentral | 1399 | |||||
| Brenda | 850 | 229525 | 229526 | 62722 | 170144 | 30240 |
| Rhea | 44423 | |||||
| ChemicalBook | CB8249322 | |||||
| Guide to Pharmacology | 6822 | |||||
| rxnorm | DROXIA | HYDREA | HYDROXYUREA | SIKLOS | ||
| PubChem: Drugs of the Future | 12014598 | |||||
| KEGG Ligand | C07044 | |||||
| ChEBI | 44423 | |||||
| ZINC | ZINC000008034120 |
