Hydroxyprogesterone Caproate

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Molecule Structure

Scientific Name

Hydroxyprogesterone Caproate

Description of the Drug

Hydroxyprogesterone caproate is a synthetic progestin used for the prevention of spontaneous preterm births in singleton pregnancies in women who have previously had a spontaneous preterm birth.

Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB06789

Brand Name(s)

Delalutin, Hydroxyprogesterone caproate, Makena, Makena (autoinjector), Makena preservative free, Proluton depot

Company Owner(s)

Aspen Pharma Usa Inc, Bristol Myers Squibb, Covis Pharma Gmbh, Sun Pharmaceutical Industries Ltd, Aspen Global Inc, American Regent Inc, Amag Pharma Usa Inc, Eugia Pharma Specialities Ltd, Allergan Sales Llc, Slayback Pharma Llc

Mechanism(s) Of Action

Target Name Target Type Action Type Target ChEMBL ID
Progesterone receptor SINGLE PROTEIN AGONIST CHEMBL208

Unichem Links

SureChEMBL SCHEMBL5330
DrugBank DB06789
PubChem: Thomson Pharma 15007174
PubChem 169870
Nikkaji J6.891H
BindingDB 70293
EPA CompTox Dashboard DTXSID6043915
DrugCentral 4189
ChemicalBook CB1702877
rxnorm MAKENA
KEGG Ligand C08148
ChEBI 5812
ZINC ZINC000004083606