Hydrochlorothiazide
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Scientific Name
Hydrochlorothiazide
Description of the Drug
Hydrochlorothiazide is a thiazide diuretic used to treat edema associated with a number of conditions, and hypertension.
Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB00999
http://www.drugbank.ca/drugs/DB00999
Brand Name(s)
Apo-hydro, Esidrex, Esidrix, Hydrochlorothiazide, Hydrochlorothiazide intensol, Hydro-d, Hydrodiuril, Hydrosaluric, Microzide, Oretic, Zide
Company Owner(s)
Dava Pharmaceuticals Inc, Pharmeral Inc, Glaxosmithkline, Invagen Pharmaceuticals Inc, Watson Laboratories Inc, Halsey Drug Co Inc, Ascot Hosp Pharmaceuticals Inc Div Travenol Laboratories Inc, Abbvie Inc, Aurolife Pharma Llc, Teva Pharmaceuticals Usa
Mechanism(s) Of Action
| Target Name | Target Type | Action Type | Target ChEMBL ID |
|---|---|---|---|
| Thiazide-sensitive sodium-chloride cotransporter | SINGLE PROTEIN | INHIBITOR | CHEMBL1876 |
Clinical Trial(s)
Unichem Links
| SureChEMBL | SCHEMBL9349 | |||
| PharmGKB | PA449899 | |||
| Human Metabolome Database | HMDB0001928 | |||
| DrugBank | DB00999 | |||
| PubChem: Thomson Pharma | 14873640 | |||
| PubChem | 3639 | |||
| Mcule | MCULE-6585933943 | |||
| LINCS | LSM-5308 | |||
| Nikkaji | J1.920H | |||
| PDBe | HCZ | |||
| BindingDB | 13076 | |||
| EPA CompTox Dashboard | DTXSID2020713 | |||
| DrugCentral | 1385 | |||
| Brenda | 197373 | 153401 | 3163 | 154385 |
| ChemicalBook | CB31564779 | CB5383966 | ||
| Guide to Pharmacology | 4836 | |||
| rxnorm | MICROZIDE | HYDROCHLOROTHIAZIDE | LOTENSIN HCT | |
| KEGG Ligand | C07041 | |||
| ChEBI | 5778 | |||
| ZINC | ZINC000000896569 |
