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Scientific Name: Haloperidol
Brand Name: Haldol
Company Owner: Ortho mcneil pharmaceutical, Ortho mcneil pharmaceutical inc, Duramed pharmaceuticals inc sub barr laboratories inc, Lederle laboratories div american cyanamid co, Mutual pharmaceutical co inc, Mylan pharmaceuticals inc, Par pharmaceutical inc, Purepac pharmaceutical co, Quantum pharmics ltd, Roxane laboratories inc, Royce laboratories inc, Sandoz inc, Scs pharmaceuticals, Vintage pharmaceuticals llc, Watson laboratories inc, Zydus pharmaceuticals usa inc, Ortho mcneil janssen pharmaceutical inc, App pharmaceuticals llc, Bedford laboratories div ben venue laboratories inc, Claris lifesciences ltd, Hospira inc, Sandoz canada inc, Teva parenteral medicines inc, Alpharma uspd inc, Morton grove pharmaceuticals inc, Pharmaceutical assoc inc div beach products, Silarx pharmaceuticals inc, Teva pharmaceuticals usa inc, Teva pharmaceuticals usa, Ortho mcneil janssen pharmaceuticals inc, Abraxis pharmaceutical products, Akorn strides llc, Gland pharma ltd, Marsam pharmaceuticals llc, Smith and nephew solopak div smith and nephew, Solopak medical products inc, Solopak laboratories inc, Actavis mid atlantic llc
Mechanism Of Action While haloperidol has demonstrated pharmacologic activity at a number of receptors in the brain, it exerts its antipsychotic effect through its strong antagonism of the dopamine receptor (mainly D2) , particularly within the mesolimbic and mesocortical systems of the brain. Schizophrenia is theorized to be caused by a hyperdopaminergic state within the limbic system of the brain.
Description of the Drug: Haloperidol is an antipsychotic agent used to treat schizophrenia and other psychoses, as well as symptoms of agitation, irritability, and delirium.
Protein Data Bank:
Source: DrugBank Online – DrugBank.com. Retrieved 2023-01-23 from https://go.drugbank.com/drugs/DB00502