Molecule Structure

Scientific Name

Gefitinib

Description of the Drug

Gefitinib is a tyrosine kinase inhibitor used as first-line therapy to treat non-small cell lung carcinoma (NSCLC) that meets certain genetic mutation criteria.

Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB00317

Brand Name(s)

Iressa

Company Owner(s)

Astrazeneca Uk Ltd, Astrazeneca Pharmaceuticals Lp

Mechanism(s) Of Action

Target Name Target Type Action Type Target ChEMBL ID
Epidermal growth factor receptor erbB1 SINGLE PROTEIN INHIBITOR CHEMBL203

Unichem Links

Atlas gefitinib
SureChEMBL SCHEMBL7866
PharmGKB PA131301952
Human Metabolome Database HMDB0014462
DrugBank DB00317
PubChem: Thomson Pharma 14833109
PubChem 123631
Mcule MCULE-6951584187
LINCS LSM-1098
Nikkaji J1.437.124I
PDBe IRE
BindingDB 5447
EPA CompTox Dashboard DTXSID8041034
DrugCentral 1282
Brenda 57709 229468 17786 21851 229469
ChemicalBook CB8120056
Guide to Pharmacology 4941
rxnorm GEFITINIB IRESSA
PubChem: Drugs of the Future 12015033
ChEBI 49668
ZINC ZINC000019632614