Ganciclovir
Back to search| Scientific Name: | Ganciclovir |
| Brand Name: | Cytovene, Zirgan |
| Company Owner: | Roche palo alto llc, Ranbaxy laboratories ltd, Bausch and lomb inc, App pharmaceuticals llc, Bedford laboratories div ben venue laboratories inc |
| Mechanism Of Action | Ganciclovir’s antiviral activity inhibits virus replication. This inhibitory action is highly selective as the drug must be converted to the active form by a virus-encoded cellular enzyme, thymidine kinase (TK) . TK catalyzes phosphorylation of ganciclovir to the monophosphate, which is then subsequently converted into the diphosphate by cellular guanylate kinase and into the triphosphate by a number of cellular enzymes. |
| Description of the Drug: | Ganciclovir is a DNA polymerase inhibitor used to treat cytomegalovirus and herpetic keratitis of the eye. |
| Protein Data Bank: |
Source: DrugBank Online – DrugBank.com. Retrieved 2023-01-23 from https://go.drugbank.com/drugs/DB01004
