Fosfomycin
Back to search| Scientific Name: | Fosfomycin |
| Brand Name: | Monurol |
| Company Owner: | Zambon spa italy |
| Mechanism Of Action | Fosfomycin exerts its bactericidal effects by binding covalently to a cysteine in the active site of the UDP-N-acetylglucosamine enolpyruvyl transferase (MurA) enzyme, rendering it inactive. By preventing MurA from catalyzing the condensation of phosphoenolpyruvate (PEP) with UDP-N-acetylglucosamine (UNAG) , fosfomycin inhibits the production of the peptidoglycan precursor UDP N-acetylmuramic acid (UDP-MurNAc) . |
| Description of the Drug: | Fosfomycin is a broad spectrum antibiotic used to treat uncomplicated urinary tract infections. |
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Source: DrugBank Online – DrugBank.com. Retrieved 2023-01-23 from https://go.drugbank.com/drugs/DB00828
