Back to search
Scientific Name: Flurbiprofen
Brand Name: Not Available
Company Owner: Pharmacia and upjohn co, Caraco pharmaceutical laboratories ltd, Ivax pharmaceuticals inc sub teva pharmaceuticals usa, Mylan pharmaceuticals inc, Pliva inc, Sandoz inc, Teva pharmaceuticals usa inc, Theragen inc, Bausch and lomb inc, Allergan pharmaceutical
Mechanism Of Action Similar to other NSAIAs, the anti-inflammatory effect of flurbiprofen occurs via reversible inhibition of cyclooxygenase (COX) , the enzyme responsible for the conversion of arachidonic acid to prostaglandin G2 (PGG2) and PGG2 to prostaglandin H2 (PGH2) in the prostaglandin synthesis pathway. This effectively decreases the concentration of prostaglandins involved in inflammation, pain, swelling and fever. Flurbiprofen is a non-selective COX inhibitor and inhibits the activity of both COX-1 and -2. It is also one of the most potent NSAIAs in terms of prostaglandin inhibitory activity.
Description of the Drug: Flurbiprofen is an NSAID used to treat the signs and symptoms of osteoarthritis and rheumatoid arthritis.
Protein Data Bank: Not Available
Source: DrugBank Online – DrugBank.com. Retrieved 2023-01-23 from https://go.drugbank.com/drugs/DB00712