Fluorouracil
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Scientific Name
Fluorouracil
Description of the Drug
Fluorouracil is a pyrimidine analog used to treat basal cell carcinomas, and as an injection in palliative cancer treatment.
Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB00544
http://www.drugbank.ca/drugs/DB00544
Brand Name(s)
5.f.u., Accusite, Actikerall, Adrucil, Carac, Efudex, Efudix, Fluoroplex, Fluorouracil, Fluoro-uracil roche, Tolak
Company Owner(s)
Marchar Laboratories Inc Ltd, Elorac Inc, Ebewe Pharma Ges Mbh Nfg Kg, Mylan Pharmaceuticals Inc, Bedford Laboratories Div Ben Venue Laboratories Inc, Fresenius Kabi Usa Llc, Novast Laboratories Ltd, Accord Healthcare Inc, Mayne Pharma Llc, Sagent Pharmaceuticals Inc
Mechanism(s) Of Action
| Target Name | Target Type | Action Type | Target ChEMBL ID |
|---|---|---|---|
| Thymidylate synthase | SINGLE PROTEIN | INHIBITOR | CHEMBL1952 |
| RNA | NUCLEIC-ACID | INHIBITOR | CHEMBL2311222 |
| DNA | NUCLEIC-ACID | INHIBITOR | CHEMBL2311221 |
Clinical Trial(s)
Unichem Links
| Atlas | 5-fluorouracil | 5-fluourouracil | ||||
| SureChEMBL | SCHEMBL3646 | |||||
| PharmGKB | PA128406956 | |||||
| Human Metabolome Database | HMDB0014684 | |||||
| DrugBank | DB00544 | |||||
| PubChem: Thomson Pharma | 15218968 | |||||
| PubChem | 3385 | |||||
| Mcule | MCULE-6338086431 | |||||
| NMRShiftDB | 20027309 | |||||
| LINCS | LSM-4261 | |||||
| Nikkaji | J4.489J | |||||
| PDBe | URF | |||||
| BindingDB | 50340677 | |||||
| EPA CompTox Dashboard | DTXSID2020634 | |||||
| DrugCentral | 26 | |||||
| Brenda | 229065 | 155282 | 51649 | 229064 | 812 | |
| ChemicalBook | CB8162744 | |||||
| Guide to Pharmacology | 4789 | |||||
| rxnorm | EFUDEX | TOLAK | ADRUCIL | CARAC | FLUOROPLEX | FLUOROURACIL |
| KEGG Ligand | C07649 | |||||
| ChEBI | 46345 | |||||
| ZINC | ZINC000038212689 |
