Flunisolide

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Scientific Name: Flunisolide
Brand Name: Not Available
Company Owner: Roche palo alto llc, Acton pharmaceuticals inc, Apotex inc richmond hill, Bausch and lomb pharmaceuticals inc, Qpharma llc, Ivax research inc, Teva branded pharmaceutical products r and d inc
Mechanism Of Action Flunisolide is a glucocorticoid receptor agonist. The antiinflammatory actions of corticosteroids are thought to involve lipocortins, phospholipase A2 inhibitory proteins which, through inhibition arachidonic acid, control the biosynthesis of prostaglandins and leukotrienes. The immune system is suppressed by corticosteroids due to a decrease in the function of the lymphatic system, a reduction in immunoglobulin and complement concentrations, the precipitation of lymphocytopenia, and interference with antigen-antibody binding. Flunisolide binds to plasma transcortin, and it becomes active when it is not bound to transcortin.
Description of the Drug: Flunisolide is an inhaled corticosteroid used as a prophylactic therapy in the maintenance treatment of asthma.
Protein Data Bank: Not Available
Source: DrugBank Online – DrugBank.com. Retrieved 2023-01-23 from https://go.drugbank.com/drugs/DB00180