Fluciclovine (18F)
Back to search| Scientific Name: | Fluciclovine (18F) |
| Brand Name: | Axumin |
| Company Owner: | Not Available |
| Mechanism Of Action | Fluciclovine is transported into the prostate cancer cells via ASCT2 and LAT1 transporters. The activity of LAT1 gets increased in acidic pH, condition that is developed intra-tumorally at certain size. The uptake of fluciclovine presents an androgen-dependent dynamic in hormone sensitive cells. |
| Description of the Drug: | Fluciclovine (18F) is a radiolabelled L-leucine derivative used to image tumors, especially in the prostate. |
| Protein Data Bank: | Not Available |
Source: DrugBank Online – DrugBank.com. Retrieved 2023-01-23 from https://go.drugbank.com/drugs/DB13146
