Flortaucipir F-18
Back to searchScientific Name: | Flortaucipir F-18 |
Brand Name: | Not Available |
Company Owner: | Not Available |
Mechanism Of Action | Alzheimer’s disease is a progressive neurodegenerative disease characterized by the build-up of hyperphosphorylated tau protein aggregates. Hyperphosphorylated tau forms dimers termed paired helical filaments (PHFs) , which aggregate further to form neurofibrillary tangles (NFTs) associated with neurodegeneration and severity of Alzheimer’s symptoms. |
Description of the Drug: | Flortaucipir F-18 is a small lipophilic tracer containing [18F]fluoride capable of crossing the blood-brain barrier and binding to aggregated tau protein; used in PET imaging for the diagnosis of Alzheimer’s disease. |
Protein Data Bank: | Not Available |
Source: DrugBank Online – DrugBank.com. Retrieved 2023-01-23 from https://go.drugbank.com/drugs/DB14914