Flortaucipir F-18

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Scientific Name: Flortaucipir F-18
Brand Name: Not Available
Company Owner: Not Available
Mechanism Of Action Alzheimer’s disease is a progressive neurodegenerative disease characterized by the build-up of hyperphosphorylated tau protein aggregates. Hyperphosphorylated tau forms dimers termed paired helical filaments (PHFs) , which aggregate further to form neurofibrillary tangles (NFTs) associated with neurodegeneration and severity of Alzheimer’s symptoms.
Description of the Drug: Flortaucipir F-18 is a small lipophilic tracer containing [18F]fluoride capable of crossing the blood-brain barrier and binding to aggregated tau protein; used in PET imaging for the diagnosis of Alzheimer’s disease.
Protein Data Bank: Not Available
Source: DrugBank Online – DrugBank.com. Retrieved 2023-01-23 from https://go.drugbank.com/drugs/DB14914