Fenfluramine
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Scientific Name
Fenfluramine
Description of the Drug
Fenfluramine is fenfluramine is a phenethylamine that is structurally similar to serotonin. Due to its ability to increase extracellular serotonin levels, modulate serotonergic and other neurologic receptors, and control neurotransmission, it is effective in treating pharmacoresistant seizures.
Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB00574
http://www.drugbank.ca/drugs/DB00574
Brand Name(s)
Not Available
Company Owner(s)
Zogenix Inc
Mechanism(s) Of Action
| Target Name | Target Type | Action Type | Target ChEMBL ID |
|---|---|---|---|
| Serotonin 2c (5-HT2c) receptor | SINGLE PROTEIN | AGONIST | CHEMBL225 |
| Serotonin 1d (5-HT1d) receptor | SINGLE PROTEIN | AGONIST | CHEMBL1983 |
| Sigma opioid receptor | SINGLE PROTEIN | ANTAGONIST | CHEMBL287 |
Clinical Trial(s)
Unichem Links
| SureChEMBL | SCHEMBL16215 | |
| PharmGKB | PA164747936 | PA449592 |
| Human Metabolome Database | HMDB0252200 | |
| DrugBank | DB00574 | |
| PubChem: Thomson Pharma | 15172399 | |
| PubChem | 3337 | |
| Nikkaji | J5.760F | |
| BindingDB | 84738 | |
| EPA CompTox Dashboard | DTXSID4023044 | |
| DrugCentral | 1150 | |
| ChemicalBook | CB0314194 | |
| Guide to Pharmacology | 4613 | |
| rxnorm | FENFLURAMINE | FENFLURAMINE HYDROCHLORIDE |
| KEGG Ligand | C06996 | |
| ChEBI | 5000 |
