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Scientific Name: Famotidine
Brand Name: Duexis, Duo Fusion, Fluxid, Good Sense Acid Reducer, Pepcid, Pepcid Complete, Zantac Reformulated Aug 2022
Company Owner: Lupin ltd, Navinta llc, Salix pharmaceuticals inc, Akorn strides llc, Apotex inc richmond hill, Apothecon inc div bristol myers squibb, App pharmaceuticals llc, Baxter healthcare corp anesthesia and critical care, Baxter healthcare corp, Bedford laboratories div ben venue laboratories inc, Hospira inc, Ben venue laboratories inc, Claris lifesciences ltd, Abbott laboratories, Baxter healthcare internati0nal specialty therapies div, Merck research laboratories div merck co inc, L perrigo co, Schwarz pharma inc, Actavis elizabeth llc, Alembic ltd, Apotex inc, Carlsbad technology inc, Dr reddys laboratories ltd, Genpharm inc, Ivax pharmaceuticals inc sub teva pharmaceuticals usa, Mutual pharmaceutical co inc, Mylan pharmaceuticals inc, Perrigo co, Ranbaxy laboratories inc, Sandoz inc, Teva pharmaceuticals usa inc, Watson laboratories inc, Wockhardt ltd, Wockhardt americas inc
Mechanism Of Action Histamine acts as a local hormone that stimulates the acid output by parietal cells via a paracrine mechanism. Neuroendocrine cells called enterochromaffin-like (ECL) cells lie close to the parietal cells and regulate the basal secretion of histamine. Histamine release is also promoted from stimulation by acetylcholine and gastrin, a peptide hormone. Gastrin (G) cells release gastrin, which works on CCK
Description of the Drug: Famotidine is a histamine H2 receptor antagonist used to treat duodenal ulcers, benign gastric ulcers, GERD, and Zollinger-Ellison syndrome.
Protein Data Bank: Not Available
Source: DrugBank Online – DrugBank.com. Retrieved 2023-01-23 from https://go.drugbank.com/drugs/DB00927