Ezetimibe
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Scientific Name
Ezetimibe
Description of the Drug
Ezetimibe is a cholesterol absorption inhibitor used to lower total cholesterol, LDL-C, Apo-B, and non-HDL-C in primary hyperlipidemia and familial cholesterolemia.
Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB00973
http://www.drugbank.ca/drugs/DB00973
Brand Name(s)
Ezetimibe, Ezetrol, Zetia
Company Owner(s)
Alkem Laboratories Ltd, Watson Laboratories Inc, Dr Reddys Laboratories Sa, Zydus Pharmaceuticals Usa Inc, Esperion Therapeutics Inc, Althera Pharmaceuticals Llc, Aurobindo Pharma Ltd, Ani Pharmaceuticals Inc, Accord Healthcare Inc, Organon Llc A Sub Of Organon And Co
Mechanism(s) Of Action
| Target Name | Target Type | Action Type | Target ChEMBL ID |
|---|---|---|---|
| Niemann-Pick C1-like protein 1 | SINGLE PROTEIN | INHIBITOR | CHEMBL2027 |
Clinical Trial(s)
Unichem Links
| SureChEMBL | SCHEMBL2871 | |
| PharmGKB | PA10816 | |
| Human Metabolome Database | HMDB0015108 | |
| DrugBank | DB00973 | |
| PubChem: Thomson Pharma | 14928749 | 14879623 |
| PubChem | 150311 | |
| Mcule | MCULE-4417284526 | |
| LINCS | LSM-5536 | |
| Nikkaji | J900.924H | |
| PDBe | H56 | |
| BindingDB | 50371521 | |
| EPA CompTox Dashboard | DTXSID1044223 | |
| DrugCentral | 1125 | |
| Brenda | 151435 | |
| ChemicalBook | CB7380787 | |
| Guide to Pharmacology | 6816 | |
| rxnorm | EZETIMIBE | ZETIA |
| PubChem: Drugs of the Future | 12014979 | |
| ChEBI | 49040 | |
| ZINC | ZINC000003810860 |
