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Scientific Name: Etravirine
Brand Name: Intelence
Company Owner: Not Available
Mechanism Of Action Etravirine exerts its effects via direct inhibition of the reverse transcriptase enzyme of human immunodeficiency virus type 1 (HIV-1) . It directly binds reverse transcriptase and consequently blocks DNA-dependent and RNA-dependent polymerase activity. Etravirine does not inhibit human DNA polymerase alpha, beta or gamma.
Description of the Drug: Etravirine is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used in the treatment of HIV-1 infections in combination with other antiretroviral agents.
Protein Data Bank:
Source: DrugBank Online – Retrieved 2023-01-23 from