Etelcalcetide

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Scientific Name: Etelcalcetide
Brand Name: Parsabiv
Company Owner: Not Available
Mechanism Of Action Etelcalcetide is a calcimimetic agent that allosterically modulates the calcium-sensing receptor (CaSR) . Etelcalcetide binds to the CaSR and enhances activation of the receptor by extracellular calcium. Activation of the CaSR on parathyroid chief cells decreases PTH secretion.
Description of the Drug: Etelcalcetide is a calcium sensing receptor agonist used to treat secondary hyperparathyroidism in patients with chronic kidney disease who require hemodialysis.
Protein Data Bank: Not Available
Source: DrugBank Online – DrugBank.com. Retrieved 2023-01-23 from https://go.drugbank.com/drugs/DB12865