Estrone sulfate

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Scientific Name: Estrone sulfate
Brand Name: Not Available
Company Owner: Not Available
Mechanism Of Action Estradiol enters target cells freely (e. g. , female organs, breasts, hypothalamus, pituitary) and interacts with a target cell receptor. When the estrogen receptor has bound its ligand it can enter the nucleus of the target cell, and regulate gene transcription which leads to formation of messenger RNA. The mRNA interacts with ribosomes to produce specific proteins that express the effect of estradiol upon the target cell. Estrogens increase the hepatic synthesis of sex hormone binding globulin (SHBG) , thyroid-binding globulin (TBG) , and other serum proteins and suppress follicle-stimulating hormone (FSH) from the anterior pituitary.
Description of the Drug: Estrone sulfate is an estrogen used as monotherapy or in several combination hormone replacement products for managing menopause symptoms and hormone disorders.
Protein Data Bank: Not Available
Source: DrugBank Online – DrugBank.com. Retrieved 2023-01-23 from https://go.drugbank.com/drugs/DB04574