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Scientific Name: Esketamine
Brand Name: Spravato
Company Owner: Not Available
Mechanism Of Action Esketamine, the S-enantiomer of racemic ketamine, is a non-selective, non-competitive antagonist of the N-methyl-D-aspartate (NMDA) receptor, an ionotropic glutamate receptor. The exact mechanism by which esketamine acts as an antidepressant is unknown. The primary circulating metabolite of esketamine (
Description of the Drug: Esketamine is a NMDA receptor antagonist used for treatment-resistant depression.
Protein Data Bank:
Source: DrugBank Online – Retrieved 2023-01-23 from