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Scientific Name: Ertugliflozin
Brand Name: Segluromet, Steglatro, Steglujan
Company Owner: Not Available
Mechanism Of Action As part of a normal process, the glucose from the blood is filtered for excretion and reabsorbed in the glomerulus so less than one percent of this glucose is excreted in the urine. The reabsorption is mediated by the sodium-dependent glucose cotransporter (SGLT) , mainly the type 2 which is responsible for 90% of the reabsorbed glucose. Ertugliflozin is a small inhibitor of the SGLT2 and its activity increases glucose excretion, reducing hyperglycemia without the requirement of excessive insulin secretion.
Description of the Drug: Ertugliflozin is a SGLT2 inhibitor used to treat type 2 diabetes mellitus.
Protein Data Bank: Not Available
Source: DrugBank Online – Retrieved 2023-01-23 from