Eplerenone

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Molecule Structure

Scientific Name

Eplerenone

Description of the Drug

Eplerenone is an aldosterone receptor antagonist used to improve survival of patients with symptomatic heart failure and to reduce blood pressure.

Source: DrugBank Online – DrugBank.com. Retrieved 2023-02-07 from
http://www.drugbank.ca/drugs/DB00700

Brand Name(s)

Eplerenone, Inspra

Company Owner(s)

Piramal Healthcare Uk Ltd, Sandoz Inc, Chartwell Rx Sciences Llc, Upjohn Us 2 Llc, Prasco Llc Dba Prasco Laboratories, Accord Healthcare Inc, Breckenridge Pharmaceutical Inc

Mechanism(s) Of Action

Target Name Target Type Action Type Target ChEMBL ID
Mineralocorticoid receptor SINGLE PROTEIN ANTAGONIST CHEMBL1994

Unichem Links

SureChEMBL SCHEMBL21515
Human Metabolome Database HMDB0014838
WDI CGP-30083
DrugBank DB00700
PubChem: Thomson Pharma 14904453 14879938
PubChem 443872
LINCS LSM-42771
Nikkaji J1.494.952F
PDBe YNU
BindingDB 50318300
EPA CompTox Dashboard DTXSID2046094
DrugCentral 1032
Brenda 196826
Guide to Pharmacology 2876
GSRS f609dd4d-05bc-41ba-a702-9e687fac9133
rxnorm INSPRA EPLERENONE
PubChem: Drugs of the Future 12015198
KEGG Ligand C12512
ChEBI 31547
ZINC ZINC000003985982