Eplerenone
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Scientific Name
Eplerenone
Description of the Drug
Eplerenone is an aldosterone receptor antagonist used to improve survival of patients with symptomatic heart failure and to reduce blood pressure.
Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB00700
http://www.drugbank.ca/drugs/DB00700
Brand Name(s)
Eplerenone, Inspra
Company Owner(s)
Breckenridge Pharmaceutical Inc, Kartha Pharmaceuticals Inc, Piramal Healthcare Uk Ltd, Sandoz Inc, Chartwell Rx Sciences Llc, Accord Healthcare Inc, Westminster Pharmaceuticals Llc, Upjohn Us 2 Llc, Prasco Llc Dba Prasco Laboratories
Mechanism(s) Of Action
Target Name | Target Type | Action Type | Target ChEMBL ID |
---|---|---|---|
Mineralocorticoid receptor | SINGLE PROTEIN | ANTAGONIST | CHEMBL1994 |
Clinical Trial(s)
Unichem Links
SureChEMBL | SCHEMBL21515 | |
Human Metabolome Database | HMDB0014838 | |
DrugBank | DB00700 | |
PubChem: Thomson Pharma | 14904453 | 14879938 |
PubChem | 443872 | |
LINCS | LSM-42771 | |
Nikkaji | J1.494.952F | |
PDBe | YNU | |
BindingDB | 50318300 | |
EPA CompTox Dashboard | DTXSID2046094 | |
DrugCentral | 1032 | |
Brenda | 196826 | |
Guide to Pharmacology | 2876 | |
rxnorm | INSPRA | EPLERENONE |
PubChem: Drugs of the Future | 12015198 | |
KEGG Ligand | C12512 | |
ChEBI | 31547 | |
ZINC | ZINC000003985982 |