Entacapone

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Molecule Structure

Scientific Name

Entacapone

Description of the Drug

Entacapone is a selective reversible catechol-O-methyltransferase inhibitor for the treatment of Parkinson’s disease.

Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB00494

Brand Name(s)

Comtan, Comtess, Entacapone

Company Owner(s)

Sunshine Lake Pharma Co Ltd, Ajanta Pharma Ltd, Alembic Pharmaceuticals Ltd, Orion Pharma, Macleods Pharmaceuticals Ltd, Sun Pharmaceutical Industries Ltd, Aurobindo Pharma Ltd, Wockhardt Ltd, Mylan Pharmaceuticals Inc, Atlantide Pharmaceuticals Ag

Mechanism(s) Of Action

Target Name Target Type Action Type Target ChEMBL ID
Catechol O-methyltransferase SINGLE PROTEIN INHIBITOR CHEMBL2023

Unichem Links

SureChEMBL SCHEMBL34504
PharmGKB PA164748726
Human Metabolome Database HMDB0012226
DrugBank DB00494
PubChem: Thomson Pharma 14776335
PubChem 5281081
LINCS LSM-43240
PDBe PD9
BindingDB 50108879
EPA CompTox Dashboard DTXSID5046439
DrugCentral 1018
Brenda 17740
ChemicalBook CB5726435
Guide to Pharmacology 6647
rxnorm COMTAN ENTACAPONE
PubChem: Drugs of the Future 12014660
KEGG Ligand C07943
ChEBI 4798
ZINC ZINC000035342787