Scientific Name: Enalapril
Brand Name: Epaned, Vaseretic, Vasotec
Company Owner: Apotex inc, Apothecon inc div bristol myers squibb, Ivax pharmaceuticals inc sub teva pharmaceuticals usa, Krka dd novo mesto, Lek pharmaceuticals d d, Mylan pharmaceuticals inc, Ranbaxy laboratories ltd, Sandoz inc, Taro pharmaceutical industries ltd, Teva pharmaceuticals usa inc, Watson laboratories inc, Wockhardt americas inc, Biovail laboratories international srl, Bedford laboratories div ben venue laboratories inc, Hikma farmaceutica (portugal) sa, Hospira inc, Teva parenteral medicines inc
Mechanism Of Action The renin-angiotensin-aldosterone system (RAAS) is a signaling pathway that works in synergism with the sympathetic system to regulate blood pressure and fluid and electrolyte homeostasis. Activation of this system upon stimulation by different factors, such as low blood pressure and nerve impulses, leads to increased release of norepinephrine (NE) from sympathetic nerve terminals and effects on the vascular growth, vasoconstriction, and salt retention in the kidneys.
Description of the Drug: Enalapril is a prodrug of an ACE inhibitor used to treat hypertension and congestive heart failure.
Protein Data Bank: Not Available
Source: DrugBank Online – DrugBank.com. Retrieved 2023-01-23 from https://go.drugbank.com/drugs/DB00584