Elexacaftor
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Scientific Name
Elexacaftor
Description of the Drug
Elexacaftor is a small molecule CFTR corrector used in combination with tezacaftor and ivacaftor for the treatment of cystic fibrosis patients with one F508del-CFTR mutation.
Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB15444
http://www.drugbank.ca/drugs/DB15444
Brand Name(s)
Not Available
Company Owner(s)
Vertex Pharmaceuticals Inc
Mechanism(s) Of Action
| Target Name | Target Type | Action Type | Target ChEMBL ID |
|---|---|---|---|
| Cystic fibrosis transmembrane conductance regulator | SINGLE PROTEIN | POSITIVE MODULATOR | CHEMBL4051 |
Clinical Trial(s)
Unichem Links
| SureChEMBL | SCHEMBL20239811 |
| Human Metabolome Database | HMDB0304881 |
| DrugBank | DB15444 |
| PubChem | 134587348 |
| PDBe | WJX |
| DrugCentral | 5372 |
| ChemicalBook | CB94848184 |
| Guide to Pharmacology | 10552 |
| rxnorm | ELEXACAFTOR |
