Molecule Structure

Scientific Name

Efavirenz

Description of the Drug

Efavirenz is a non-nucleoside reverse transcriptase inhibitor used to treat HIV infection or prevent the spread of HIV.

Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB00625

Brand Name(s)

Efavirenz, Sustiva, Sustiva 600

Company Owner(s)

Cipla Ltd, Bristol Myers Squibb Co, Mylan Laboratories Ltd, Macleods Pharmaceuticals Ltd, Laurus Labs Ltd, Hetero Labs Ltd Unit Iii, Aurobindo Pharma Ltd, Hetero Labs Ltd Unit V, Gilead Sciences Llc, Mylan Pharmaceuticals Inc

Mechanism(s) Of Action

Target Name Target Type Action Type Target ChEMBL ID
Human immunodeficiency virus type 1 reverse transcriptase SINGLE PROTEIN INHIBITOR CHEMBL247

Unichem Links

SureChEMBL SCHEMBL37762
PharmGKB PA449441
Human Metabolome Database HMDB0014763
DrugBank DB00625
PubChem: Thomson Pharma 14850291
PubChem 64139
Mcule MCULE-3949811498
LINCS LSM-5526
Nikkaji J727.577C
PDBe EFZ
BindingDB 2483
EPA CompTox Dashboard DTXSID9046029
DrugCentral 989
Brenda 1704 42381
ChemicalBook CB7181559
Guide to Pharmacology 11287
rxnorm EFAVIRENZ SUSTIVA
PubChem: Drugs of the Future 12014858
KEGG Ligand C08088
ChEBI 119486
ZINC ZINC000002020233