Duloxetine
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Scientific Name
Duloxetine
Description of the Drug
Duloxetine is a serotonin norepinephrine reuptake inhibitor used to treat generalized anxiety disorder, neuropathic pain, osteoarthritis, and stress incontinence.
Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB00476
http://www.drugbank.ca/drugs/DB00476
Brand Name(s)
Not Available
Company Owner(s)
Sunshine Lake Pharma Co Ltd, Alkem Laboratories Ltd, Macleods Pharmaceuticals Ltd, Anchen Pharmaceuticals Inc, Zydus Pharmaceuticals Usa Inc, Prinston Pharmaceutical Inc, Inventia Healthcare Ltd, Torrent Pharmaceuticals Ltd, Ajanta Pharma Ltd, Eli Lilly And Co
Mechanism(s) Of Action
| Target Name | Target Type | Action Type | Target ChEMBL ID |
|---|---|---|---|
| Serotonin transporter | SINGLE PROTEIN | INHIBITOR | CHEMBL228 |
| Norepinephrine transporter | SINGLE PROTEIN | INHIBITOR | CHEMBL222 |
Clinical Trial(s)
Unichem Links
| SureChEMBL | SCHEMBL8291 | ||
| PharmGKB | PA10066 | ||
| Human Metabolome Database | HMDB0014619 | ||
| DrugBank | DB00476 | ||
| PubChem: Thomson Pharma | 14849439 | 14873633 | |
| PubChem | 60835 | ||
| LINCS | LSM-3591 | ||
| Nikkaji | J550.708A | ||
| PDBe | 29E | ||
| BindingDB | 84745 | ||
| EPA CompTox Dashboard | DTXSID6048385 | ||
| DrugCentral | 972 | ||
| Brenda | 167769 | ||
| ChemicalBook | CB8670379 | ||
| Guide to Pharmacology | 202 | ||
| rxnorm | DULOXETINE | CYMBALTA | DULOXETINE HYDROCHLORIDE |
| ChEBI | 36795 | ||
| ZINC | ZINC000001536779 |
