Drotaverine
Back to search| Scientific Name: | Drotaverine |
| Brand Name: | Not Available |
| Company Owner: | Not Available |
| Mechanism Of Action | Drotaverine is a selective inhibitor of phosphodiesterase 4 (PDE4) , which is an enzyme responsible for the degradation of cyclic adenosine monophosphate (cAMP) . Inhibition of PDE4 leads to elevated levels of cAMP, leading to smooth muscle relaxation. Recent research showed that low levels of cAMP have been associated with brain tumorigenesis, leading to the investigation of PDE4 inhibitors as potential anticancer agents. |
| Description of the Drug: | Drotaverine is a phosphodiesterase-4 inhibitor used to alleviate gastrointestinal and genitourinary smooth muscle spasms. |
| Protein Data Bank: | Not Available |
Source: DrugBank Online – DrugBank.com. Retrieved 2023-01-23 from https://go.drugbank.com/drugs/DB06751
