Doxorubicin
Back to search| Scientific Name: | Doxorubicin |
| Brand Name: | Adriamycin, Doxil, Myocet |
| Company Owner: | Ortho biotech products lp, Pharmacia and upjohn co, App pharmaceuticals llc, Bedford laboratories div ben venue laboratories inc, Pharmachemie bv, Teva parenteral medicines inc, Bristol myers squibb co |
| Mechanism Of Action | Doxorubicin has antimitotic and cytotoxic activity through a number of proposed mechanisms of action: Doxorubicin forms complexes with DNA by intercalation between base pairs, and it inhibits topoisomerase II activity by stabilizing the DNA-topoisomerase II complex, preventing the religation portion of the ligation-religation reaction that topoisomerase II catalyzes. |
| Description of the Drug: | Doxorubicin is a medication used to treat various cancers and Kaposi’s Sarcoma. |
| Protein Data Bank: |
|
Source: DrugBank Online – DrugBank.com. Retrieved 2023-01-23 from https://go.drugbank.com/drugs/DB00997
