Scientific Name: Dosulepin
Brand Name: Not Available
Company Owner: Not Available
Mechanism Of Action By binding to noradrenaline transporter (NAT) and serotonin transporter (SERT) in an equipotent manner and inhibiting the reuptake activity, dosulepin increases the free levels of noradrenaline and 5HT at the synaptic cleft. It is shown that the main metabolite northiaden is a more potent inhibitor of noradrenaline uptake than the parent drug
Description of the Drug: Dosulepin is a tricyclic antidepressant commonly used only in patients for whom alternative therapies are ineffective due to its toxicity potential.
Protein Data Bank: Not Available
Source: DrugBank Online – Retrieved 2023-01-23 from