Scientific Name: Dopamine
Brand Name: Not Available
Company Owner: Abbott laboratories hosp products div, Abraxis pharmaceutical products, Astrazeneca lp, Baxter healthcare corp anesthesia and critical care, Hospira inc, International medication system, Luitpold pharmaceuticals inc, Smith and nephew solopak div smith and nephew, Teva parenteral medicines inc, Warner chilcott div warner lambert co, B braun medical inc, Baxter healthcare corp
Mechanism Of Action Dopamine is a precursor to norepinephrine in noradrenergic nerves and is also a neurotransmitter in certain areas of the central nervous system. Dopamine produces positive chronotropic and inotropic effects on the myocardium, resulting in increased heart rate and cardiac contractility. This is accomplished directly by exerting an agonist action on beta-adrenoceptors and indirectly by causing release of norepinephrine from storage sites in sympathetic nerve endings. In the brain, dopamine acts as an agonist to the five dopamine receptor subtypes (D1, D2, D3, D4, D5) .
Description of the Drug: Dopamine is a catecholamine neurotransmitter used to treat hemodynamic imbalances, poor perfusion of vital organs, low cardiac output, and hypotension.
Protein Data Bank:
Source: DrugBank Online – DrugBank.com. Retrieved 2023-01-23 from https://go.drugbank.com/drugs/DB00988