Dofetilide

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Molecule Structure

Scientific Name

Dofetilide

Description of the Drug

Dofetilide is a class III antiarrhythmic drug used for the maintenance of normal sinus rhythm and cardioversion in cases of atrial fibrillation and atrial flutter.

Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB00204

Brand Name(s)

Dofetilide, Tikosyn

Company Owner(s)

Pfizer Pharmaceuticals Production Corp Ltd, Teva Pharmaceuticals Usa Inc, Msn Laboratories Private Ltd, Sigmapharm Laboratories Llc, Sun Pharmaceutical Industries Ltd, Prinston Pharmaceutical Inc, Mayne Pharma Inc, Novast Laboratories Ltd, Aurobindo Pharma Ltd, Accord Healthcare Inc

Mechanism(s) Of Action

Target Name Target Type Action Type Target ChEMBL ID
HERG SINGLE PROTEIN BLOCKER CHEMBL240

Unichem Links

SureChEMBL SCHEMBL16135
PharmGKB PA449389
Human Metabolome Database HMDB0014349
DrugBank DB00204
PubChem: Thomson Pharma 14832836
PubChem 71329
LINCS LSM-5925
Nikkaji J291.759I
BindingDB 50031720
EPA CompTox Dashboard DTXSID5046433
DrugCentral 942
ChemicalBook CB3381832
Guide to Pharmacology 2604
rxnorm DOFETILIDE TIKOSYN
PubChem: Drugs of the Future 12014163
KEGG Ligand C07751
ChEBI 4681
ZINC ZINC000000596731