Diphenhydramine

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Molecule Structure

Scientific Name

Diphenhydramine

Description of the Drug

Diphenhydramine is a H1 receptor antihistamine used in the treatment of seasonal allergies, and various allergic reactions including sneezing, runny nose, itchy/watery eyes, itching of nose or throat, pruritus, urticaria, insect bites/stings, and allergic rashes.

Source: DrugBank Online – DrugBank.com. Retrieved 2023-02-07 from
http://www.drugbank.ca/drugs/DB01075

Brand Name(s)

Not Available

Company Owner(s)

Bayer Healthcare Consumer Care, Fosun Pharma Usa Inc, Lannett Co Inc, Watson Laboratories Inc, Wyeth Ayerst Laboratories, Impax Laboratories Inc, Ivax Pharmaceuticals Inc Sub Teva Pharmaceuticals Usa, Usl Pharma Inc, Lnk International Inc, Private Formulations Inc

Mechanism(s) Of Action

Target Name Target Type Action Type Target ChEMBL ID
Histamine H1 receptor SINGLE PROTEIN ANTAGONIST CHEMBL231

Unichem Links

SureChEMBL SCHEMBL4064
PharmGKB PA449349
Human Metabolome Database HMDB0001927
WDI DIPHENTAN DIPHENHYD
DrugBank DB01075
PubChem: Thomson Pharma 14749996
PubChem 3100
Mcule MCULE-6260910826
LINCS LSM-5581
Nikkaji J1.390K
PDBe 2PM
BindingDB 50017674
EPA CompTox Dashboard DTXSID4022949
DrugCentral 916
Brenda 155303 36366
ChemicalBook CB6196202
Guide to Pharmacology 1224
GSRS 80f9a846-fbae-499d-96a1-2c1c0c09d05b
rxnorm DIPHENHYDRAMINE HYDROCHLORIDE BENADRYL DIPHENHYDRAMINE TANNATE CALADRYL DYTUSS NYTOL DIPHENHYDRAMINE CITRATE DIPHENHYDRAMINE
KEGG Ligand C06960
ChEBI 4636
ZINC ZINC000000020244