Scientific Name: Difenoxin
Brand Name: Motofen
Company Owner: Not Available
Mechanism Of Action Difenoxin acts as an antidiarrheal by activating peripheral opioid receptors in the small intestine and thereby inhibiting peristalsis. However, research has suggested that non-opioid receptor pathways exist. This would explain the potent antidiarrheal effects of difenoxin despite only limited opioid action [1].
Description of the Drug: Difenoxin is an antidiarrheal agent used as an adjunct for the management of acute nonspecific diarrhea and acute exacerbations of chronic functional diarrhea.
Protein Data Bank: Not Available
Source: DrugBank Online – Retrieved 2023-01-23 from