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Scientific Name: Diethylpropion
Brand Name: Tepanil
Company Owner: Sanofi aventis us llc, Watson pharmaceuticals, 3m pharmaceuticals inc, Corepharma llc, Sandoz inc, Teva pharmaceuticals usa inc, Tg united labs llc, Ucb inc, Watson laboratories inc
Mechanism Of Action Diethylpropion is an amphetamine that stimulates neurons to release or maintain high levels of a particular group of neurotransmitters known as catecholamines; these include dopamine and norepinephrine. High levels of these catecholamines tend to suppress hunger signals and appetite. Diethylpropion (through catecholamine elevation) may also indirectly affect leptin levels in the brain. It is theorized that diethylpropion can raise levels of leptin which signal satiety. It is also theorized that increased levels of the catecholamines are partially responsible for halting another chemical messenger known as neuropeptide Y. This peptide initiates eating, decreases energy expenditure, and increases fat storage.
Description of the Drug: Diethylpropion is an appetite suppressant used for the short term treatment of exogenous obesity in addition to calorie restriction.
Protein Data Bank: Not Available
Source: DrugBank Online – Retrieved 2023-01-23 from