Dexrazoxane

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Molecule Structure

Scientific Name

Dexrazoxane

Description of the Drug

Dexrazoxane is a cytoprotective drug used to prevent and improve cardiomyopathy associated with doxorubicin treatment for metastatic breast cancer.

Source: DrugBank Online – DrugBank.com. Retrieved 2023-02-07 from
http://www.drugbank.ca/drugs/DB00380

Brand Name(s)

Cardioxane, Zinecard

Company Owner(s)

Hikma Pharmaceuticals Usa Inc, Clinigen Inc, Pfizer Inc, Gland Pharma Ltd, Eugia Pharma Specialities Ltd

Mechanism(s) Of Action

Target Name Target Type Action Type Target ChEMBL ID
Iron METAL SEQUESTERING AGENT CHEMBL2363058
DNA topoisomerase II PROTEIN FAMILY INHIBITOR CHEMBL2094255

Unichem Links

SureChEMBL SCHEMBL18400
PharmGKB PA449259
Human Metabolome Database HMDB0014524
WDI ICRF-187
DrugBank DB00380
PubChem: Thomson Pharma 14872576 14774896
PubChem 71384
LINCS LSM-5248
Nikkaji J22.227E
EPA CompTox Dashboard DTXSID3040647
DrugCentral 839
Brenda 156066 227946 139374 16717 17799
ChemicalBook CB2251448
Guide to Pharmacology 7330
GSRS 06f3b671-bbc9-4679-92df-7c9774e19464
rxnorm DEXRAZOXANE HYDROCHLORIDE TOTECT DEXRAZOXANE ZINECARD
ChEBI 50223
ZINC ZINC000087515509