Dexrazoxane
Back to searchMolecule Structure
Scientific Name
Dexrazoxane
Description of the Drug
Dexrazoxane is a cytoprotective drug used to prevent and improve cardiomyopathy associated with doxorubicin treatment for metastatic breast cancer.
Source: DrugBank Online – DrugBank.com. Retrieved 2023-02-07 from
http://www.drugbank.ca/drugs/DB00380
http://www.drugbank.ca/drugs/DB00380
Brand Name(s)
Cardioxane, Zinecard
Company Owner(s)
Hikma Pharmaceuticals Usa Inc, Clinigen Inc, Pfizer Inc, Gland Pharma Ltd, Eugia Pharma Specialities Ltd
Mechanism(s) Of Action
| Target Name | Target Type | Action Type | Target ChEMBL ID |
|---|---|---|---|
| Iron | METAL | SEQUESTERING AGENT | CHEMBL2363058 |
| DNA topoisomerase II | PROTEIN FAMILY | INHIBITOR | CHEMBL2094255 |
Clinical Trial(s)
Unichem Links
| SureChEMBL | SCHEMBL18400 | ||||
| PharmGKB | PA449259 | ||||
| Human Metabolome Database | HMDB0014524 | ||||
| WDI | ICRF-187 | ||||
| DrugBank | DB00380 | ||||
| PubChem: Thomson Pharma | 14872576 | 14774896 | |||
| PubChem | 71384 | ||||
| LINCS | LSM-5248 | ||||
| Nikkaji | J22.227E | ||||
| EPA CompTox Dashboard | DTXSID3040647 | ||||
| DrugCentral | 839 | ||||
| Brenda | 156066 | 227946 | 139374 | 16717 | 17799 |
| ChemicalBook | CB2251448 | ||||
| Guide to Pharmacology | 7330 | ||||
| GSRS | 06f3b671-bbc9-4679-92df-7c9774e19464 | ||||
| rxnorm | DEXRAZOXANE HYDROCHLORIDE | TOTECT | DEXRAZOXANE | ZINECARD | |
| ChEBI | 50223 | ||||
| ZINC | ZINC000087515509 |
