Deferasirox

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Scientific Name: Deferasirox
Brand Name: Exjade, Jadenu
Company Owner: Not Available
Mechanism Of Action Two molecules of deferasirox are capable of binding to 1 atom of iron. Deferasirox works in treating iron toxicity by binding trivalent (ferric) iron (for which it has a strong affinity) , forming a stable complex which is eliminated via the kidneys.
Description of the Drug: Deferasirox is an iron chelator used to treat chronic iron overload caused by blood transfusions. Also used in patients with non-transfusion-dependent thalassemia syndromes, and in patients with elevated liver iron concentration and serum ferritin.
Protein Data Bank:
Source: DrugBank Online – DrugBank.com. Retrieved 2023-01-23 from https://go.drugbank.com/drugs/DB01609