Deferasirox

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Molecule Structure

Scientific Name

Deferasirox

Description of the Drug

Deferasirox is an iron chelator used to treat chronic iron overload caused by blood transfusions. Also used in patients with non-transfusion-dependent thalassemia syndromes, and in patients with elevated liver iron concentration and serum ferritin.

Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB01609

Brand Name(s)

Deferasirox, Exjade, Jadenu, Jadenu sprinkle

Company Owner(s)

Teva Pharmaceuticals Usa Inc, Alkem Laboratories Ltd, Msn Laboratories Private Ltd, Cipla Ltd, Alembic Pharmaceuticals Ltd, Piramal Healthcare Uk Ltd, Celltrion Inc, Sun Pharmaceutical Industries Ltd, Actavis Elizabeth Llc, Bionpharma Inc

Mechanism(s) Of Action

Target Name Target Type Action Type Target ChEMBL ID
Iron METAL CHELATING AGENT CHEMBL2363058

Unichem Links

SureChEMBL SCHEMBL61756
Human Metabolome Database HMDB0015547
DrugBank DB01609
PubChem: Thomson Pharma 14853198
PubChem 214348
LINCS LSM-45297
Nikkaji J1.213.542D
PDBe JBL
BindingDB 50088376
EPA CompTox Dashboard DTXSID1048596
DrugCentral 3128
rxnorm EXJADE JADENU DEFERASIROX
PubChem: Drugs of the Future 12015358
ChEBI 49005
ZINC ZINC000001481815