Deferasirox
Back to searchScientific Name: | Deferasirox |
Brand Name: | Exjade, Jadenu |
Company Owner: | Not Available |
Mechanism Of Action | Two molecules of deferasirox are capable of binding to 1 atom of iron. Deferasirox works in treating iron toxicity by binding trivalent (ferric) iron (for which it has a strong affinity) , forming a stable complex which is eliminated via the kidneys. |
Description of the Drug: | Deferasirox is an iron chelator used to treat chronic iron overload caused by blood transfusions. Also used in patients with non-transfusion-dependent thalassemia syndromes, and in patients with elevated liver iron concentration and serum ferritin. |
Protein Data Bank: |
Source: DrugBank Online – DrugBank.com. Retrieved 2023-01-23 from https://go.drugbank.com/drugs/DB01609