Dantrolene
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Scientific Name
Dantrolene
Description of the Drug
Dantrolene is a direct-acting skeletal muscle relaxant used for the treatment of management of the fulminant hypermetabolism of skeletal muscle leading to malignant hyperthermia crisis.
Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB01219
http://www.drugbank.ca/drugs/DB01219
Brand Name(s)
Not Available
Company Owner(s)
Uswm Llc, Par Sterile Products Llc, Elite Laboratories Inc, Eugia Pharma Specialities Ltd, Eagle Pharmaceuticals Inc, Impax Laboratories Inc, Hikma Pharmaceuticals Llc
Mechanism(s) Of Action
| Target Name | Target Type | Action Type | Target ChEMBL ID |
|---|---|---|---|
| Ryanodine receptor 1 | SINGLE PROTEIN | ANTAGONIST | CHEMBL1846 |
| Ryanodine receptor 3 | SINGLE PROTEIN | ANTAGONIST | CHEMBL2062 |
Clinical Trial(s)
Unichem Links
| Atlas | dantrolene | ||||
| SureChEMBL | SCHEMBL40893 | ||||
| DrugBank | DB01219 | ||||
| PubChem: Thomson Pharma | 14899016 | ||||
| PubChem | 6914273 | ||||
| BindingDB | 50198767 | ||||
| DrugCentral | 780 | ||||
| Brenda | 18799 | ||||
| Guide to Pharmacology | 4172 | ||||
| rxnorm | DANTROLENE SODIUM | RYANODEX | DANTRIUM | DANTROLENE | REVONTO |
| KEGG Ligand | C06939 | ||||
| ZINC | ZINC000002568036 |
