Cytarabine
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Scientific Name
Cytarabine
Description of the Drug
Cytarabine is a pyrimidine nucleoside analogue used to treat acute non-lymphocytic leukemia, lymphocytic leukemia, and the blast phase of chronic myelocytic leukemia.
Source: DrugBank Online – DrugBank.com. Retrieved 2023-02-07 from
http://www.drugbank.ca/drugs/DB00987
http://www.drugbank.ca/drugs/DB00987
Brand Name(s)
Alexan, Alexan 100, Cytarabine, Cytosar, Cytosar-u, Depocyt, Depocyte, Tarabine Pfs
Company Owner(s)
Meitheal Pharmaceuticals Inc, Teva Pharmaceuticals Usa, Teva Parenteral Medicines Inc, West-Ward Pharmaceuticals International Ltd, Hospira Inc, Fresenius Kabi Usa Llc, Gland Pharma Ltd, Celator Pharmaceuticals Inc, Pacira Pharmaceuticals Inc, Hong Kong King Friend Industrial Co Ltd
Mechanism(s) Of Action
| Target Name | Target Type | Action Type | Target ChEMBL ID |
|---|---|---|---|
| RNA | NUCLEIC-ACID | INHIBITOR | CHEMBL2311222 |
| DNA | NUCLEIC-ACID | INHIBITOR | CHEMBL2311221 |
| DNA polymerase (alpha/delta/epsilon) | PROTEIN FAMILY | INHIBITOR | CHEMBL2363042 |
Clinical Trial(s)
Unichem Links
| Atlas | Ara-C | cytarabine | ||||||||||||||||||||
| SureChEMBL | SCHEMBL23152019 | SCHEMBL3140 | SCHEMBL22591193 | |||||||||||||||||||
| PharmGKB | PA449177 | |||||||||||||||||||||
| Human Metabolome Database | HMDB0015122 | HMDB0000089 | ||||||||||||||||||||
| WDI | CYTARABIN | DR9501772 | ||||||||||||||||||||
| DrugBank | DB00987 | |||||||||||||||||||||
| PubChem: Thomson Pharma | 15196510 | 14774115 | ||||||||||||||||||||
| PubChem | 6253 | |||||||||||||||||||||
| Mcule | MCULE-3945147956 | |||||||||||||||||||||
| LINCS | LSM-5470 | |||||||||||||||||||||
| Nikkaji | J2.958K | |||||||||||||||||||||
| PDBe | AR3 | |||||||||||||||||||||
| EPA CompTox Dashboard | DTXSID3022877 | |||||||||||||||||||||
| DrugCentral | 770 | |||||||||||||||||||||
| Brenda | 636 | 8126 | 229322 | 206941 | 153431 | 92674 | 18270 | 35304 | 2016 | 92471 | 93727 | 91329 | 3364 | 148756 | 32999 | 96737 | 229323 | 154421 | 151038 | 2681 | 22093 | 92473 |
| Guide to Pharmacology | 4827 | |||||||||||||||||||||
| GSRS | 2b258dc9-0ac3-44df-bc57-7712751e5cbe | |||||||||||||||||||||
| rxnorm | CYTARABINE | CYTARABINE LIPOSOME | ||||||||||||||||||||
| KEGG Ligand | C02961 | |||||||||||||||||||||
| ChEBI | 28680 | |||||||||||||||||||||
| NIH Clinical Collection | SAM001247012 | |||||||||||||||||||||
| ZINC | ZINC000003795098 |
