Cytarabine
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Scientific Name
Cytarabine
Description of the Drug
Cytarabine is a pyrimidine nucleoside analogue used to treat acute non-lymphocytic leukemia, lymphocytic leukemia, and the blast phase of chronic myelocytic leukemia.
Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB00987
http://www.drugbank.ca/drugs/DB00987
Brand Name(s)
Alexan, Alexan 100, Cytarabine, Cytosar, Cytosar-u, Depocyt, Depocyte, Tarabine Pfs
Company Owner(s)
Hong Kong King Friend Industrial Co Ltd, Fresenius Kabi Usa Llc, Mylan Laboratories Ltd, Celator Pharmaceuticals Inc, West-Ward Pharmaceuticals International Ltd, Hospira Inc, Rising Pharma Holding Inc, Gland Pharma Ltd, Teva Parenteral Medicines Inc, Meitheal Pharmaceuticals Inc
Mechanism(s) Of Action
| Target Name | Target Type | Action Type | Target ChEMBL ID |
|---|---|---|---|
| DNA polymerase (alpha/delta/epsilon) | PROTEIN FAMILY | INHIBITOR | CHEMBL2363042 |
| DNA | NUCLEIC-ACID | INHIBITOR | CHEMBL2311221 |
| RNA | NUCLEIC-ACID | INHIBITOR | CHEMBL2311222 |
Clinical Trial(s)
Unichem Links
| Atlas | cytarabine | Ara-C | |||||||||||||
| SureChEMBL | SCHEMBL23152019 | SCHEMBL22591193 | SCHEMBL3140 | ||||||||||||
| PharmGKB | PA449177 | ||||||||||||||
| Human Metabolome Database | HMDB0015122 | ||||||||||||||
| DrugBank | DB00987 | ||||||||||||||
| PubChem: Thomson Pharma | 15196510 | 14774115 | |||||||||||||
| PubChem | 6253 | ||||||||||||||
| Mcule | MCULE-3945147956 | ||||||||||||||
| NMRShiftDB | 80001531 | ||||||||||||||
| LINCS | LSM-5470 | ||||||||||||||
| Nikkaji | J2.958K | ||||||||||||||
| PDBe | AR3 | ||||||||||||||
| BindingDB | 50087289 | ||||||||||||||
| EPA CompTox Dashboard | DTXSID3022877 | ||||||||||||||
| DrugCentral | 770 | ||||||||||||||
| Brenda | 2016 | 18270 | 229322 | 148756 | 35304 | 32999 | 154421 | 92473 | 151038 | 206941 | 153431 | 229323 | 92471 | 2681 | 22093 |
| Guide to Pharmacology | 4827 | ||||||||||||||
| rxnorm | CYTARABINE LIPOSOME | CYTARABINE | |||||||||||||
| KEGG Ligand | C02961 | ||||||||||||||
| ChEBI | 28680 | ||||||||||||||
| ZINC | ZINC000003795098 |
