Cytarabine

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Molecule Structure

Scientific Name

Cytarabine

Description of the Drug

Cytarabine is a pyrimidine nucleoside analogue used to treat acute non-lymphocytic leukemia, lymphocytic leukemia, and the blast phase of chronic myelocytic leukemia.

Source: DrugBank Online – DrugBank.com. Retrieved 2023-02-07 from
http://www.drugbank.ca/drugs/DB00987

Brand Name(s)

Alexan, Alexan 100, Cytarabine, Cytosar, Cytosar-u, Depocyt, Depocyte, Tarabine Pfs

Company Owner(s)

Meitheal Pharmaceuticals Inc, Teva Pharmaceuticals Usa, Teva Parenteral Medicines Inc, West-Ward Pharmaceuticals International Ltd, Hospira Inc, Fresenius Kabi Usa Llc, Gland Pharma Ltd, Celator Pharmaceuticals Inc, Pacira Pharmaceuticals Inc, Hong Kong King Friend Industrial Co Ltd

Mechanism(s) Of Action

Target Name Target Type Action Type Target ChEMBL ID
RNA NUCLEIC-ACID INHIBITOR CHEMBL2311222
DNA NUCLEIC-ACID INHIBITOR CHEMBL2311221
DNA polymerase (alpha/delta/epsilon) PROTEIN FAMILY INHIBITOR CHEMBL2363042

Unichem Links

Atlas Ara-C cytarabine
SureChEMBL SCHEMBL23152019 SCHEMBL3140 SCHEMBL22591193
PharmGKB PA449177
Human Metabolome Database HMDB0015122 HMDB0000089
WDI CYTARABIN DR9501772
DrugBank DB00987
PubChem: Thomson Pharma 15196510 14774115
PubChem 6253
Mcule MCULE-3945147956
LINCS LSM-5470
Nikkaji J2.958K
PDBe AR3
EPA CompTox Dashboard DTXSID3022877
DrugCentral 770
Brenda 636 8126 229322 206941 153431 92674 18270 35304 2016 92471 93727 91329 3364 148756 32999 96737 229323 154421 151038 2681 22093 92473
Guide to Pharmacology 4827
GSRS 2b258dc9-0ac3-44df-bc57-7712751e5cbe
rxnorm CYTARABINE CYTARABINE LIPOSOME
KEGG Ligand C02961
ChEBI 28680
NIH Clinical Collection SAM001247012
ZINC ZINC000003795098