Cyclosporine
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Scientific Name
Cyclosporine
Description of the Drug
Cyclosporine is a steroid-sparing immunosuppressant used in organ and bone marrow transplants as well as inflammatory conditions such as ulcerative colitis, rheumatoid arthritis, and atopic dermatitis.
Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB00091
http://www.drugbank.ca/drugs/DB00091
Brand Name(s)
Capimune, Capsorin, Cequa, Cyclosporine, Deximune, Gengraf, Ikervis, Neoral, Optimmune, Restasis, Restasis multidose, Sandimmun, Sandimmune, Sangcya, Vanquoral, Verkazia
Company Owner(s)
Apotex Inc, Wockhardt Bio Ag, Padagis Us Llc, Sandoz Inc, Pharmaceutical Associates Inc, Sun Pharmaceutical Industries Ltd, Santen Inc, Abbvie Inc, Mylan Pharmaceuticals Inc, Mayne Pharma Llc
Mechanism(s) Of Action
| Target Name | Target Type | Action Type | Target ChEMBL ID |
|---|---|---|---|
| Cyclophilin A | SINGLE PROTEIN | MODULATOR | CHEMBL1949 |
Clinical Trial(s)
Unichem Links
| Atlas | ciclosporin | cyclosporine A | ||||||||
| SureChEMBL | SCHEMBL4442 | |||||||||
| DrugBank | DB00091 | |||||||||
| PubChem: Thomson Pharma | 14817125 | 14817127 | ||||||||
| PubChem | 5284373 | |||||||||
| NMRShiftDB | 80025006 | |||||||||
| LINCS | LSM-42883 | |||||||||
| Nikkaji | J34.321H | |||||||||
| BindingDB | 50022815 | |||||||||
| EPA CompTox Dashboard | DTXSID0020365 | |||||||||
| DrugCentral | 760 | |||||||||
| Metabolights | MTBLC4031 | |||||||||
| Brenda | 88208 | 170708 | ||||||||
| ChemicalBook | CB5163816 | |||||||||
| Guide to Pharmacology | 1024 | |||||||||
| rxnorm | CEQUA | RESTASIS | NEORAL | ATOPICA | CYCLOSPORINE MICROEMULSION | OPTIMMUNE | SANDIMMUNE | CYCLOSPORINE, MODIFIED | CYCLOSPORINE | GENGRAF |
| PubChem: Drugs of the Future | 12013381 | |||||||||
| ChEBI | 4031 |
