Scientific Name: Colistin
Brand Name: Cortisporin-TC
Company Owner: Parke davis div warner lambert co
Mechanism Of Action Colistin is a surface active agent which penetrates into and disrupts the bacterial cell membrane. Colistin is polycationic and has both hydrophobic and lipophilic moieties. It interacts with the bacterial cytoplasmic membrane, changing its permeability. This effect is bactericidal. There is also evidence that polymyxins enter the cell and precipitate cytoplasmic components, primarily ribosomes.
Description of the Drug: Colistin is a polymyxin antibiotic used to treat bacterial infections caused by susceptible Gram negative bacteria.
Protein Data Bank: Not Available
Source: DrugBank Online – Retrieved 2023-01-23 from