Cobicistat

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Molecule Structure

Scientific Name

Cobicistat

Description of the Drug

Cobicistat is a CYP3A inhibitor used to increase the systemic exposure of atazanavir or darunavir in combination with other antiretroviral agents in the treatment of HIV-1 infection.

Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB09065

Brand Name(s)

Tybost

Company Owner(s)

Bristol-Myers Squibb Co, Janssen Products Lp, Gilead Sciences Inc

Mechanism(s) Of Action

Target Name Target Type Action Type Target ChEMBL ID
Cytochrome P450 3A PROTEIN FAMILY INHIBITOR CHEMBL2364675

Unichem Links

SureChEMBL SCHEMBL2736227
PharmGKB PA166165092
DrugBank DB09065
PubChem: Thomson Pharma 57245301
PubChem 25151504
LINCS LSM-45771
Nikkaji J3.033.505H
BindingDB 50447471
EPA CompTox Dashboard DTXSID00143269
DrugCentral 4299
ChemicalBook CB62627692
Guide to Pharmacology 7535
rxnorm TYBOST COBICISTAT
ChEBI 72291
ZINC ZINC000085537014