Clozapine
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Scientific Name
Clozapine
Description of the Drug
Clozapine is an atypical or second-generation antipsychotic drug used in treatment-resistant schizophrenia and to decrease suicide risk in schizophrenic patients.
Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB00363
http://www.drugbank.ca/drugs/DB00363
Brand Name(s)
Clozapine, Clozaril, Fazaclo, Fazaclo odt, Versacloz, Zaponex
Company Owner(s)
Ivax Pharmaceuticals Inc Sub Teva Pharmaceuticals Usa, Par Pharmaceutical, Sun Pharmaceutical Industries Inc, Sandoz Inc, Heritage Life Sciences Barbados Inc, Accord Healthcare Inc, Aurobindo Pharma Ltd, Mylan Pharmaceuticals Inc, Barr Laboratories Inc, Teva Pharmaceuticals Usa
Mechanism(s) Of Action
| Target Name | Target Type | Action Type | Target ChEMBL ID |
|---|---|---|---|
| Dopamine D2 receptor | SINGLE PROTEIN | ANTAGONIST | CHEMBL217 |
| Serotonin 2a (5-HT2a) receptor | SINGLE PROTEIN | ANTAGONIST | CHEMBL224 |
Clinical Trial(s)
Unichem Links
| Atlas | clozapine | |||
| SureChEMBL | SCHEMBL8397 | |||
| Human Metabolome Database | HMDB0014507 | |||
| DrugBank | DB00363 | |||
| PubChem: Thomson Pharma | 14826474 | |||
| PubChem | 135398737 | |||
| NMRShiftDB | 20061832 | |||
| LINCS | LSM-2823 | |||
| Nikkaji | J8.061F | |||
| BindingDB | 50001884 | |||
| EPA CompTox Dashboard | DTXSID5022855 | |||
| DrugCentral | 722 | |||
| Brenda | 4685 | |||
| ChemicalBook | CB7776111 | |||
| Guide to Pharmacology | 38 | |||
| rxnorm | VERSACLOZ | CLOZARIL | CLOZAPINE | FAZACLO |
| PubChem: Drugs of the Future | 12013419 | |||
| KEGG Ligand | C06924 | |||
| ChEBI | 3766 | |||
| ZINC | ZINC000019796155 |
