Scientific Name: Clozapine
Brand Name: Clozaril, Fazaclo, Versacloz
Company Owner: Azur pharma international iii ltd, Caraco pharmaceutical laboratories ltd, Ivax pharmaceuticals inc sub teva pharmaceuticals usa, Mylan pharmaceuticals inc, Par pharmaceutical, Sandoz inc, Novartis pharmaceuticals corp
Mechanism Of Action Clozapine’s antipsychotic action is likely mediated through a combination of antogistic effects at D2 receptors in the mesolimbic pathway and 5-HT2A receptors in the frontal cortex. D2 antagonism relieves positive symptoms while 5-HT2A antagonism alleviates negative symptoms.
Description of the Drug: Clozapine is an antipsychotic drug used in treatment resistant schizophrenia and to decrease suicide risk in schizophrenic patients.
Protein Data Bank: Not Available
Source: DrugBank Online – DrugBank.com. Retrieved 2023-01-23 from https://go.drugbank.com/drugs/DB00363