Clozapine
Back to search| Scientific Name: | Clozapine |
| Brand Name: | Clozaril, Fazaclo, Versacloz |
| Company Owner: | Azur pharma international iii ltd, Caraco pharmaceutical laboratories ltd, Ivax pharmaceuticals inc sub teva pharmaceuticals usa, Mylan pharmaceuticals inc, Par pharmaceutical, Sandoz inc, Novartis pharmaceuticals corp |
| Mechanism Of Action | Clozapine’s antipsychotic action is likely mediated through a combination of antogistic effects at D2 receptors in the mesolimbic pathway and 5-HT2A receptors in the frontal cortex. D2 antagonism relieves positive symptoms while 5-HT2A antagonism alleviates negative symptoms. |
| Description of the Drug: | Clozapine is an antipsychotic drug used in treatment resistant schizophrenia and to decrease suicide risk in schizophrenic patients. |
| Protein Data Bank: | Not Available |
Source: DrugBank Online – DrugBank.com. Retrieved 2023-01-23 from https://go.drugbank.com/drugs/DB00363
