Clofarabine
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Scientific Name
Clofarabine
Description of the Drug
Clofarabine is a purine nucleoside used to treat relapsed or refractory acute lymphoblastic leukemia in patients 1 to 21 years old.
Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB00631
http://www.drugbank.ca/drugs/DB00631
Brand Name(s)
Clolar, Evoltra
Company Owner(s)
Genzyme Corp, Msn Laboratories Private Ltd, Mylan Laboratories Ltd, Abon Pharmaceuticals Llc, Hospira Inc, Novast Laboratories Ltd, Gland Pharma Ltd, Accord Healthcare Inc, Meitheal Pharmaceuticals Inc, Dr Reddys Laboratories Ltd
Mechanism(s) Of Action
| Target Name | Target Type | Action Type | Target ChEMBL ID |
|---|---|---|---|
| DNA | NUCLEIC-ACID | INHIBITOR | CHEMBL2311221 |
| DNA polymerase (alpha/delta/epsilon) | PROTEIN FAMILY | INHIBITOR | CHEMBL2363042 |
| Ribonucleoside-diphosphate reductase RR1 | PROTEIN COMPLEX GROUP | INHIBITOR | CHEMBL2095215 |
Clinical Trial(s)
Unichem Links
| SureChEMBL | SCHEMBL9040 | ||||
| PharmGKB | PA164754863 | ||||
| Human Metabolome Database | HMDB0014769 | ||||
| DrugBank | DB00631 | ||||
| PubChem: Thomson Pharma | 14800615 | 14800616 | |||
| PubChem | 119182 | ||||
| Mcule | MCULE-2276059681 | ||||
| LINCS | LSM-45668 | ||||
| Nikkaji | J457.798A | ||||
| PDBe | CFB | ||||
| BindingDB | 50247921 | ||||
| EPA CompTox Dashboard | DTXSID5046437 | ||||
| DrugCentral | 691 | ||||
| Brenda | 143944 | 5855 | 136540 | 34457 | 128097 |
| Guide to Pharmacology | 6802 | ||||
| rxnorm | CLOLAR | CLOFARABINE | |||
| PubChem: Drugs of the Future | 12014412 | ||||
| ChEBI | 681569 | ||||
| ZINC | ZINC000003798247 |
