Cladribine

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Molecule Structure

Scientific Name

Cladribine

Description of the Drug

Cladribine is a purine antimetabolite used for the management of relapsing forms of Multiple Sclerosis (MS), used in patients who have not responded to or who were unable to tolerate alternative MS drugs.

Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB00242

Brand Name(s)

Cladribine, Leustat, Leustatin, Litak, Mavenclad

Company Owner(s)

Fresenius Kabi Usa Llc, Mylan Laboratories Ltd, Hikma Pharmaceuticals Usa Inc, Hisun Pharmaceutical (Hangzhou) Co Ltd, Emd Serono Inc, Janssen Pharmaceuticals Inc

Mechanism(s) Of Action

Target Name Target Type Action Type Target ChEMBL ID
DNA NUCLEIC-ACID INHIBITOR CHEMBL2311221

Unichem Links

SureChEMBL SCHEMBL3775
PharmGKB PA449027
Human Metabolome Database HMDB0014387
DrugBank DB00242
PubChem: Thomson Pharma 14897807 14799875
PubChem 20279
LINCS LSM-5976
Nikkaji J446.344G
PDBe CL9
BindingDB 38920
EPA CompTox Dashboard DTXSID8022828
DrugCentral 667
Brenda 143941 2913 5796 8475
Guide to Pharmacology 4799
rxnorm MAVENCLAD CLADRIBINE
PubChem: Drugs of the Future 99431527
ChEBI 567361
ZINC ZINC000003798064