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Scientific Name: Cinacalcet
Brand Name: Mimpara, Sensipar
Company Owner: Amgen inc
Mechanism Of Action Cinacalcet directly lowers parathyroid hormone levels by increasing the sensitivity of the calcium sensing receptors to activation by extracellular calcium, resulting in the inhibition of PTH secretion. The reduction in PTH is associated with a concomitant decrease in serum calcium levels.
Description of the Drug: Cinacalcet is a calcium sensing receptor agonist used to treat secondary hyperparathyroidism in chronic kidney disease and hypercalcemia in parathyroid carcinoma.
Protein Data Bank:
Source: DrugBank Online – Retrieved 2023-01-23 from