Cilastatin

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Molecule Structure

Scientific Name

Cilastatin

Description of the Drug

Cilastatin is a renal dehydropeptidase inhibitor used to prevent degradation of imipenem. Both medications are used together to treat a variety of infections.

Source: DrugBank Online – DrugBank.com. Retrieved 2023-02-07 from
http://www.drugbank.ca/drugs/DB01597

Brand Name(s)

Not Available

Company Owner(s)

Merck Sharp And Dohme Corp A Sub Of Merck And Co Inc, Merck And Co Inc, Hq Specialty Pharma Corp, Hospira Inc, Acs Dobfar Spa

Mechanism(s) Of Action

Target Name Target Type Action Type Target ChEMBL ID
Renal dipeptidase SINGLE PROTEIN INHIBITOR CHEMBL1989

Unichem Links

SureChEMBL SCHEMBL37051
PharmGKB PA448998
Human Metabolome Database HMDB0015535
WDI CILASTATI
DrugBank DB01597
PubChem: Thomson Pharma 14803328 15447933
PubChem 6435415
LINCS LSM-43242
Nikkaji J32.849I
EPA CompTox Dashboard DTXSID8048238
DrugCentral 640
Metabolights MTBLC3697
Guide to Pharmacology 5166
GSRS 475670a4-db36-4bc7-9027-610333eb545f
rxnorm CILASTATIN SODIUM PRIMAXIN CILASTATIN
KEGG Ligand C01675
ChEBI 3697
ZINC ZINC000004095696