Cilastatin
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Scientific Name
Cilastatin
Description of the Drug
Cilastatin is a renal dehydropeptidase inhibitor used to prevent degradation of imipenem. Both medications are used together to treat a variety of infections.
Source: DrugBank Online – DrugBank.com. Retrieved 2023-02-07 from
http://www.drugbank.ca/drugs/DB01597
http://www.drugbank.ca/drugs/DB01597
Brand Name(s)
Not Available
Company Owner(s)
Merck Sharp And Dohme Corp A Sub Of Merck And Co Inc, Merck And Co Inc, Hq Specialty Pharma Corp, Hospira Inc, Acs Dobfar Spa
Mechanism(s) Of Action
| Target Name | Target Type | Action Type | Target ChEMBL ID |
|---|---|---|---|
| Renal dipeptidase | SINGLE PROTEIN | INHIBITOR | CHEMBL1989 |
Clinical Trial(s)
Unichem Links
| SureChEMBL | SCHEMBL37051 | ||
| PharmGKB | PA448998 | ||
| Human Metabolome Database | HMDB0015535 | ||
| WDI | CILASTATI | ||
| DrugBank | DB01597 | ||
| PubChem: Thomson Pharma | 14803328 | 15447933 | |
| PubChem | 6435415 | ||
| LINCS | LSM-43242 | ||
| Nikkaji | J32.849I | ||
| EPA CompTox Dashboard | DTXSID8048238 | ||
| DrugCentral | 640 | ||
| Metabolights | MTBLC3697 | ||
| Guide to Pharmacology | 5166 | ||
| GSRS | 475670a4-db36-4bc7-9027-610333eb545f | ||
| rxnorm | CILASTATIN SODIUM | PRIMAXIN | CILASTATIN |
| KEGG Ligand | C01675 | ||
| ChEBI | 3697 | ||
| ZINC | ZINC000004095696 |
