Chlorthalidone

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Molecule Structure

Scientific Name

Chlorthalidone

Description of the Drug

Chlorthalidone is a diuretic used to treat hypertension or edema caused by heart failure, renal failure, hepatic cirrhosis, estrogen therapy, and other conditions.

Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB00310

Brand Name(s)

Chlorthalidone, Hygroton, Thalitone

Company Owner(s)

Dava Pharmaceuticals Inc, Alkem Laboratories Ltd, Sun Pharmaceutical Industries Inc, Watson Laboratories Inc, Abbott Laboratories Pharmaceutical Products Div, Ascot Hosp Pharmaceuticals Inc Div Travenol Laboratories Inc, Kv Pharmaceutical Co, Mankind Pharma Ltd, Mylan Pharmaceuticals Inc, Purepac Pharmaceutical Co

Mechanism(s) Of Action

Target Name Target Type Action Type Target ChEMBL ID
Thiazide-sensitive sodium-chloride cotransporter SINGLE PROTEIN INHIBITOR CHEMBL1876

Unichem Links

SureChEMBL SCHEMBL26234
PharmGKB PA448970
Human Metabolome Database HMDB0014455
DrugBank DB00310
PubChem: Thomson Pharma 14924761
PubChem 2732
Mcule MCULE-6661021422
LINCS LSM-1417
Nikkaji J1.476A
BindingDB 25900
EPA CompTox Dashboard DTXSID4022812
DrugCentral 625
Brenda 5949
ChemicalBook CB3233539
Guide to Pharmacology 7147
rxnorm CHLORTHALIDONE
ChEBI 3654